Boris Epel
personal webpage
Publications
Overall publications: 60+
1. Orlinskii SB, Rakhmatullin RM, Epel BM. 1994. Loop-Gap Cavities for Pulsed X-Ray Esr Spectrometers. Instrum Exp Tech+ 37:599-600.
2. Epel B, Goldfarb D. 2000. Two-dimensional pulsed TRIPLE at 95 GHz. J Magn Reson 146:196-203. [pdf]
3. Epel B, Manikandan P, Kroneck PMH, Goldfarb D. 2001. High-field ENDOR and the sign of the hyperfine coupling. Applied Magnetic Resonance 21:287-97. [pdf]
4. Epel B, Poppl A, Manikandan P, Vega S, Goldfarb D. 2001. The effect of spin relaxation on ENDOR spectra recorded at high magnetic fields and low temperatures. J Magn Reson 148:388-97. [pdf]
5. Manikandan P, Epel B, Goldfarb D. 2001. Structure of copper(II) -histidine based complexes in frozen aqueous solutions as determined from high-field pulsed electron nuclear double resonance. Inorg Chem 40:781-7. [pdf]
6. Richards JH, Fernandez CO, Cricco JA, et al. 2001. Axial ligand modulation of a low-lying excited state in the thermus Cu-A domain. J Inorg Biochem 86:400-. [pdf]
7. Slutter CE, Bardhan S, Di Bilio AJ, et al. 2001. Characterization of methionine 160 axial ligand mutants from a soluble Cu-A domain from cytochrome ba3 of thermus thermophilus. J Inorg Biochem 86:435-. [pdf]
8. Slutter CE, Gromov I, Epel B, Pecht I, Richards JH, Goldfarb D. 2001. Pulsed EPR/ENDOR characterization of perturbations of the Cu-A center ground state by axial methionine ligand mutations. Journal of the American Chemical Society 123:5325-36. [pdf]
9. Epel B, Goldfarb D. 2002. High-field ENDOR and the sign of hyperfine coupling (vol 21, pg 287, 2001). Applied Magnetic Resonance 22:135-. [pdf]
10. Epel B, Slutter CS, Neese F, et al. 2002. Electron-mediating Cu-A Centers in proteins: A comparative high field H-1 ENDOR study. Journal of the American Chemical Society 124:8152-62. [pdf]
11. Carmieli R, Manikandan P, Epel B, et al. 2003. Dynamics in the Mn2+ binding site in single crystals of concanavalin a revealed by high-field EPR spectroscopy. Biochemistry-Us 42:7863-70. [pdf]
12. Epel B, Arieli D, Baute D, Goldfarb D. 2003. Improving W-band pulsed ENDOR sensitivity-random acquisition and pulsed special TRIPLE. J Magn Reson 164:78-83. [pdf]
13. Van Doorslaer S, Jeschke G, Epel B, et al. 2003. Axial solvent coordination in "base-off" Cob(II)alamin and related Co(II)-corrinates revealed by 2D-EPR. Journal of the American Chemical Society 125:5915-27. [pdf]
14. Goldfarb D, Epel B, Zimmermann H, Jeschke G. 2004. 2D TRIPLE in orientationally disordered samples - a means to resolve and determine relative orientation of hyperfine tensors. J Magn Reson 168:75-87. [pdf]
15. Epel B, Gromov I, Stoll S, Schweiger A, Goldfarb D. 2005. Spectrometer manager: A versatile control software for pulse EPR spectrometers. Conc Magn Reson B 26B:36-45. [pdf]
16. Epel B, Schafer KO, Quentmeier A, Friedrich C, Lubitz W. 2005. Multifrequency EPR analysis of the dimanganese cluster of the putative sulfate thiohydrolase SoxB of Paracoccus pantotrophus. J Biol Inorg Chem 10:636-42. [pdf]
17. Kulik L, Epel B, Messinger J, Lubitz W. 2005. Pulse EPR, Mn-55-ENDOR and ELDOR-detected NMR of the S-2-state of the oxygen evolving complex in Photosystem II. Photosynth Res 84:347-53. [pdf]
18. Kulik LV, Epel B, Lubitz W, Messinger J. 2005. Mn-55 pulse ENDOR at 34 GHz of the S-0 and S-2 states of the oxygen-evolving complex in photosystem II. Journal of the American Chemical Society 127:2392-3. [pdf]
19. Epel B, Niklas J, Antonkine ML, Lubitz W. 2006. Absolute signs of hyperfine coupling constants as determined by pulse ENDOR of polarized radical pairs. Applied Magnetic Resonance 30:311-27. [pdf]
20. Epel B, Niklas J, Sinnecker S, Zimmermann H, Lubitz W. 2006. Phylloquinone and related radical anions studied by pulse electron nuclear double resonance spectroscopy at 34 GHz and density functional theory. Journal of Physical Chemistry B 110:11549-60. [pdf]
21. Antonkine M, Breitenstein C, Epel B, Bill E, Gartner W, Lubitz W. 2007. De Novo peptides modelling the binding sites of [4Fe-4S] clusters in photosystem I. Photosynth Res 91:282-. [pdf]
22. Kulik LV, Epel B, Lubitz W, Messinger J. 2007. Electronic structure of the Mn4OxCa cluster in the S-0 and S-2 states of the oxygen-evolving complex of photosystem II based on pulse Mn-55-ENDOR and EPR Spectroscopy. Journal of the American Chemical Society 129:13421-35. [pdf]
23. Messinger J, Kulik L, Epel B, Zem S, Yano J. 2007. Electronic and geometric structures of the Mn4OxCa cluster in the S-0 and S-2 states of the oxygen-evolving complex of photosystem II based on pulse. Photosynth Res 91:173-4. [pdf]
24. Niklas J, Epel B, Antonkine M, Sinnecker S, Pandelia M. 2007. The electron acceptor quinone A(1) of photosystem I investigated by pulse EPR and ENDOR spectroscopy. Photosynth Res 91:146-. [pdf]
25. Stoll S, Epel B, Vega S, Goldfarb D. 2007. Ligand protons in a frozen solution of copper histidine relax via a T-1e-driven three-spin mechanism. J Chem Phys 127:164511. [pdf]
26. Epel B, Sundramoorthy SV, Mailer C, Halpern HJ. 2008. A versatile high speed 250-MHz pulse imager for biomedical applications. Conc Magn Reson B 33B:163-76. [pdf]
27. Goldfarb D, Lipkin Y, Potapov A, et al. 2008. HYSCORE and DEER with an upgraded 95 GHz pulse EPR spectrometer. J Magn Reson 194:8-15. [pdf]
28. Potapov A, Epel B, Goldfarb D. 2008. A triple resonance hyperfine sublevel correlation experiment for assignment of electron-nuclear double resonance lines. J Chem Phys 128:52320-10. [pdf]
29. Antonkine ML, Koay MS, Epel B, et al. 2009. Synthesis and characterization of de novo designed peptides modelling the binding sites of [4Fe-4S] clusters in photosystem I. Bba-Bioenergetics 1787:995-1008. [pdf]
30. Niklas J, Epel B, Antonkine ML, Sinnecker S, Pandelia ME, Lubitz W. 2009. Electronic Structure of the Quinone Radical Anion A(1)(center dot-) of Photosystem I Investigated by Advanced Pulse EPR and ENDOR Techniques. Journal of Physical Chemistry B 113:10367-79. [pdf]
31. Sundramoorthy SV, Epel B, Mailer C, Halpern HJ. 2009. A Passive Dual-Circulator Based Transmit/Receive Switch for Use with Reflection Resonators in Pulse Electron Paramagnetic Resonance. Conc Magn Reson B 35B:133-8. [pdf]
32. Epel B, Haney CR, Hleihel D, Wardrip C, Barth ED, Halpern HJ. 2010. Electron paramagnetic resonance oxygen imaging of a rabbit tumor using localized spin probe delivery. Medical Physics 37:2553-9. [pdf]
33. Niklas J, Gopta O, Epel B, Lubitz W, Antonkine ML. 2010. Investigation of the Stationary and Transient A (1) (center dot-) Radical in Trp -> Phe Mutants of Photosystem I. Applied Magnetic Resonance 38:187-203. [pdf]
34. Seifi P, Epel B, Mailer C, Halpern HJ. 2010. Multiple-stepped Zeeman field offset method applied in acquiring enhanced resolution spin-echo electron paramagnetic resonance images. Medical Physics 37:5412-20. [pdf]
35. Cox N, Ames W, Epel B, et al. 2011. Electronic Structure of a Weakly Antiferromagnetically Coupled (MnMnIII)-Mn-II Model Relevant to Manganese Proteins: A Combined EPR, Mn-55-ENDOR, and DFT Study. Inorg Chem 50:8238-51. [pdf]
36. Elas M, Hleihel D, Barth ED, et al. 2011. Where It's at Really Matters: In Situ In Vivo Vascular Endothelial Growth Factor Spatially Correlates with Electron Paramagnetic Resonance pO(2) Images in Tumors of Living Mice. Molecular Imaging and Biology 13:1107-13. [pdf]
37. Epel B, Halpern HJ. 2011. Comparison of transverse and spin-lattice relaxation based electron paramagnetic resonance oxygen images. Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on Biomedical Imaging. Chicago: IEEE Xplore:754 - 7 .
38. Epel B, Sundramoorthy SV, Barth ED, Mailer C, Halpern HJ. 2011. Comparison of 250 MHz electron spin echo and continuous wave oxygen EPR imaging methods for in vivo applications. Medical Physics 38:2045-52. [pdf]
39. Epel B, Sundramoorthy SV, Halpern HJ. 2011. Retractable Loop-Gap Resonators for Electron Paramagnetic Resonance Imaging with In Situ Irradiation Capabilities. Conc Magn Reson B 39B:167-72. [pdf]
40. Feintuch A, Shimon D, Hovav Y, et al. 2011. A Dynamic Nuclear Polarization spectrometer at 95 GHz/144 MHz with EPR and NMR excitation and detection capabilities. J Magn Reson 209:136-41. [pdf]
41. Kaminker I, Florent M, Epel B, Goldfarb D. 2011. Simultaneous acquisition of pulse EPR orientation selective spectra. J Magn Reson 208:95-102. [pdf]
42. Seifi P, Epel B, Sundramoorthy SV, Mailer C, Halpern HJ. 2011. Frequency bandwidth extension by use of multiple Zeeman field offsets for electron spin-echo EPR oxygen imaging of large objects. Medical Physics 38:3062-8. [pdf]
43. Nakagawa K, Ohba Y, Epel B, Hirata H. 2012. A 9 GHz EPR Imager for Thin Materials: Application to Surface Detection. J Oleo Sci 61:451-6. [pdf]
44. Elas M, Magwood JM, Butler B, et al. 2013. EPR Oxygen Images Predict Tumor Control by a 50% Tumor Control Radiation Dose. Cancer Research 73:5328-35. [pdf]
45. Redler G, Elas M, Epel B, Barth ED, Halpern HJ. 2013. Radiation oxygen biology with pulse electron paramagnetic resonance imaging in animal tumors. Advances in experimental medicine and biology 789:399-404. [pdf]
46. Redler G, Epel B, Halpern HJ. 2013. Maximally Spaced Projection Sequencing in Electron Paramagnetic Resonance Imaging. Medical Physics 40. [pdf]
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47. Epel B, Bowman MK, Mailer C, Halpern HJ. 2014. Absolute oxygen R1e imaging in vivo with pulse electron paramagnetic resonance. Magnet Reson Med 72:362-8. [pdf]
48. Epel B, Redler G, Halpern HJ. 2014. How In Vivo EPR Measures and Images Oxygen. Advances in experimental medicine and biology 812:113-9. [pdf]
49. Majumdar S, Kotecha M, Triplett W, Epel B, Halpern H. 2014. A DTI study to probe tumor microstructure and its connection with hypoxia. Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE; 26-30 Aug. 2014. p. 738-41 [pdf].
50. Nakagawa K, Epel B. 2014. Locations of radical species in black pepper seeds investigated by CW EPR and 9 GHz EPR imaging. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy 131:342-6. [pdf]
51. Qiao ZW, Redler G, Epel B, Halpern HJ. 2014. Comparison of parabolic filtration methods for 3D filtered back projection in pulsed EPR imaging. J Magn Reson 248:42-53. [pdf]
52. Redler G, Epel B, Halpern HJ. 2014. Principal Component Analysis Enhances SNR for Dynamic Electron Paramagnetic Resonance Oxygen Imaging of Cycling Hypoxia In Vivo. Magnet Reson Med 71:440-50. [pdf]
53. Redler G, Epel B, Halpern HJ. 2014. What We Learn from In Vivo EPR Oxygen Images. Advances in experimental medicine and biology 812:121-6. [pdf]
54. Redler G, Epel B, Halpern HJ. 2014. EPR Image Based Oxygen Movies for Transient Hypoxia. Advances in experimental medicine and biology 812:127-33. [pdf]
55. Sundramoorthy SV, Epel B, Halpern HJ. 2014. Orthogonal resonators for pulse in vivo electron paramagnetic imaging at 250 MHz. J Magn Reson 240:45-51. [pdf]
56. Epel B, Halpern HJ. 2015. Comparison of pulse sequences for R-1-based electron paramagnetic resonance oxygen imaging. J Magn Reson 254:56-61. [pdf]
57. Qiao ZW, Redler GG, Epel B, Qian YH, Halpern H. 2015. Implementation of GPU-accelerated back projection for EPR imaging. J X-Ray Sci Technol 23:423-33. [pdf]
58. Redler G, Epel B, Halpern HJ. 2015. Maximally spaced projection sequencing in electron paramagnetic resonance imaging. Conc Magn Reson B 45:33-45. [pdf]
59. Redler G, Qiao ZW, Epel B, Halpern HJ. 2015. Real-time image reconstruction for pulse EPR oxygen imaging using a GPU and lookup table parameter fitting. Conc Magn Reson B 45:46-57. [pdf]
60. Epel B, Redler G, Pelizzari C, Tormyshev VM, Halpern HJ. 2016. Approaching Oxygen-Guided Intensity-Modulated Radiation Therapy. Adv Exp Med Biol 876:185-93.
61. Epel B, Redler G, Tormyshev V, Halpern HJ. 2016. Towards Human Oxygen Images with Electron Paramagnetic Resonance Imaging. Adv Exp Med Biol 876:363-9.
62. Christodoulou AG, Redler G, Clifford B, Liang ZP, Halpern, HJ, and Epel B 2016. Fast dynamic electron paramagnetic resonance (EPR) oxygen imaging using low-rank tensors. J Magn Reson 270:176-.
63. Tseytlin M, Epel B, Sundramoorthy S, Tipikin D, Halpern HJ. 2016. Decoupling of excitation and receive coils in pulsed magnetic resonance using sinusoidal magnetic field modulation. J Magn Reson 272:91-9.
64. Epel B, Sundramoorthy SV, Krzykawska-Serda M, et al. 2017. Imaging thiol redox status in murine tumors in vivo with rapid-scan electron paramagnetic resonanc. J Magn Reson 276:31-6.
65. Nakagawa K, Epel B. 2017. Investigating the Distribution of Stable Paramagnetic Species in an Apple Seed Using X-Band EPR and EPR Imaging. J Oleo Sci 66:315-9.
66. Shi YL, Quine RW, Rinard GA, et al. 2017. Triarylmethyl Radical: EPR Signal to Noise at Frequencies between 250 MHz and 1.5 GHz and Dependence of Relaxation on Radical and Salt Concentration and on Frequency. Z Phys Chem 231:923-37.
Reviews
Epel B, Halpern HJ. (2012) Electron paramagnetic resonance oxygen imaging in vivo. Electron Paramagnetic Resonance. The Royal Society of Chemistry; 2013:180-208.
Epel B, Halpern HJ. (2015) In Vivo pO2 Imaging of Tumors: Oxymetry with Very Low-Frequency Electron Paramagnetic Resonance. Methods Enzymol 564:501-27
Epel, B., Kotecha, M. and Halpern, H. J. (2017) In Vivo EPR Oxygen Imaging, in Magnetic Resonance Imaging in Tissue Engineering (eds M. Kotecha, R. L. Magin and J. J. Mao), John Wiley & Sons, Inc., Hoboken, NJ, USA
Epel, B., and Halpern, H. J. (2017) Modern EPR Spectroscopy handbook: Basic Techniques and Instrumentation, Chapter 13. Imaging.
Eaton, S.S., Shi, Y.L., Woodcock, L., Buchanan, L.A., McPeak, J., Quine, R.W., Rinard, G.A., Epel, B., Halpern, H.J., and Eaton, G.R. (2017) Rapid-scan EPR imaging. J Magn Reson 280, 140.
Patent
T1-sensitive inversion-recovery-imaging method and apparatus for EPRI, U.S. Patent Application No. 13/032,637
Recent invited talks
2016 Acceleration of time resolved EPR pO2 images using a low-rank tensor/ navigator projection image model; Multimodality image registration using a general animal immobilization platform fabricated with 3D printing, 43d Annual ISOTT Meeting, Wuhan, China, July 11-16th, 2015
2015 EPR Methodologies Enabled by Loop-Gap Resonators, National Biomedical EPR Center workshop, Milwaukee, August 21-22, 2015
2014 EPR in vivo imaging using Sinusoidal Rapid Scan, 43rd Southeastern Magnetic Resonance Conference, Tuscaloosa ,October 2014
2013 “How EPR measures and images oxygen”, 41st Annual ISOTT Meeting & EPR 2013, Dartmouth, NH
2012 “Registration of in vivo tumor EPR Oxygen Images with Histology Images of Pimonidazol Stain”, 20th JSPS International Redox Core Symposium, Fukuoka, Japan.
2011 “Rapid Electron Spin Echo Imaging of Oxygen in vivo”, 53th Rocky Mountain conference on Analytical Chemistry, EPR symposia, Snowmass, Colorado
2010 “Exploring the Limits of Electron Spin Echo in vivo Oxygen Imaging”, 52th Rocky Mountain conference on Analytical Chemistry, EPR symposia, Snowmass, Colorado